SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d5d28a7f12c89819b75fd61d75a144ea25240d784e68a28d932b018c0d46c7' 
  AND token = '8o19p1JFGym3uBe2inbSrVJaPxtMdGKXKQ34tfQqdLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}