SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd03f1ef5c68eb5d27a7a856480e8b22803fe0e715470d53a63b398ced0c2d2a1' 
  AND token = 'ZvuAo4Hn1yPKglz+ESFD32O9wLMEC6cqw7fZPkL0Wok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}