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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709ba93a7960aac06df33a8037ff48560f473ff705a9a47bb87f9fdffeb14d0a' 
  AND token = 'y7uY0mmhlDCq7nVO9ox9KPoj29+n1wxBtV3ZRPTov+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}