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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53522eed00331f12e4e9eaaed2cae9c74e045e06881857cc3e8091b771ae35db' 
  AND token = '1Drd1rZn4BNB4xkiS1dEi8M3kuA8zDUKBRT4m7g47Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}