SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1564d90735f95da3d0ae1e5ae682f9c6e4caaa4692b80cdefc37ddbbb15fc149' 
  AND token = 'ihjWEd3b7e4wtBrDxAGt75SQHKfGFFb+PLFDoCK96G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}