SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c4bf1af29ea75e25a219ba71321cc0f36b31ae64b0845a275c9f5d01d01aa9' 
  AND token = 'U+coXbZObQ03kW4EYHj1bru2+HwV7KOje0IBlovz5oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}