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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e27aba219b470bbc3c5fbfc8000dc39c0d736227c80d59c81a564f8af9c3792' 
  AND token = 'dQYin6H9T84OpsKOQcNYlH3lefbJfp7Io/RfWGP0cAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}