SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01b3f070507e994360aff024a0713191e6b5f6c4e11b9fed72540ee0d22668f' 
  AND token = 'oNSrgxp45WqcLA7Hf7W9IkA2vMzGyz5AmcID0OcAS/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}