SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b874d4ebda1ac5259055a1e0dc620c3ac6e330798267c400d3a325617636c439' 
  AND token = 'UobTs29Z0qfERbpota3nrloTHhiwCFmNqmr2JrHTVy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}