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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8acc568ccd645b1a50a1b7771f9d3cd5c9acc5b646a36de1ea56067a6e5bf52c' 
  AND token = 'bczzEfe5IgJ6EUCo5uaVikCI3JZxDnHM5P/SDuAjMw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}