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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc8d529211b5f933941c6de4f46e7fcc8ede9c0b306e0219403e8c264d84328' 
  AND token = 'iATVFedteH6OZVytKbOKCob3yHtogL7GVmYDkTtv5gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}