SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6205c073b73e37286270c845e6b8ab7e82a6b50ef883924ca206ff7ff6687e5' 
  AND token = 'otsV2AD4Sgk8zqRnxbBpfzFrUkWrlN6778hX6Dd7u7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}