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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfcdb47e96afb4615aebe81e2addc3dc20b078333f04a643e730f0c958e378ac' 
  AND token = 'e2C1e9A42hodiCQnzj10XYVMSezrIb78q0HgHr+yEFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}