SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e08dc18a966d6aebd95cf987e05c38531b0fd896955bf6c9ca40788f179e080' 
  AND token = 'i2y6qnwiRJ+RZClOqcXK+CWVbDEEn2YP8HiDCFXJU38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}