SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e9e059903910ae689284488ca05ec86cca3e315a6d15b7b403dc36343f43f5' 
  AND token = 'ZwgiA53utIuLKiTBb5w3dtObIjpsU7JqcYXdSNpnCdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}