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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0435927cf72baab4f4ede2b8bb35515e1941566812ad6397dd8fd8dbbe642f' 
  AND token = 'hZ8AFMLGmAi5NYQp/WA/tMWssLN6XD0hwwImsd/IFuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}