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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecdea9729e0efb638268d3d7a05921a7843fa0f2602a2f378c28493f3681144' 
  AND token = 'UyMky0H97KESl5MfTgx0/MYiHIdlC9f8o8sAIAyanfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}