SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e704cae5ea42343207286e0fdc48e4bd814f81536ad8395e4b157baf2a2f38e3' 
  AND token = 'ivlmqfnOJRZ/7cTBuKRcWPBkTVch8m2UlpTM0pfZgqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}