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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0422b40e6e89838a5b2d4686d410c54f4449e9d2112e15bbf9e60d34206ad031' 
  AND token = 'vqOl5/M2RvmG5a5jzjKuqQ25wlfJK2sXRfxq0UJFgQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}