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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66a195d5e0a020e251c50488d05a846b3a427e36406d5aa737447789702e072' 
  AND token = 'FOVLgJFrThc7L4eZ1z0IXvfoOSv7skRG/X4xUuZcKCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}