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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334a710a090ca7f008d533ac49e161ee3d74c67aeac981074e3260d0bb0b3346' 
  AND token = 'As+mlTiO3Mtxb3gO7QJUzu10r4z0PREuj1T/Lj09+b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}