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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8105357e6ea723fb6916f83026d0140621bd5785db4e8985059d364a04887f1b' 
  AND token = 'PyWjG+IZV143JWIudX8uWQFZSQfk1kbpJUR5N3Of8Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}