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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3375ce8d866817bd8e72c370a00b378d430f224a4cf1b4e4365e63a0862a03d' 
  AND token = '+jB/dsRM7wnDtSmSgEwPODVZ20+sYEKG9XqEMeSaA2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}