SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80a2cd192a22c4fa7cd21ca346ffd6a1e7f807c1b031adf8c967f3450932bba' 
  AND token = 'f6iaVm7stVwPrNWVemnLkAtcdVSMpL/T9KVYU7vjND8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}