SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1f5b496d0e732634873329c09261175bcc104df8ce7b62b6907620a29aecd8' 
  AND token = 'UiZ1Vn/KEpdBVwj0OUURt8I95y8BdxlHrPffpdXWiDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}