SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce15c2df159fd3cd758aec5813d66b1998facc7688d4010d094288d6aa191fe' 
  AND token = '0zV9015L0v5VMW0SyaukE1Q/6+1kED8OEEzWOoqhuqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}