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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5307ed72a5067d7573977c6fed1ec9c74cc541bf703b0cdae9e0fbb9f0157e7a' 
  AND token = 'YWMGRyVR5XzMVikJk1/QI3WHO3b5LxaX01e3P1as434=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}