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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b49bea2aa50f61275dc4c7d9ed00e70de82b66f444a0cb533dcc091b3e66c2a' 
  AND token = 'U+oz2ABng0OJLvuzDFOQM46qUDKG7HpMG2gQ6E00YK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}