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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58180bbf5509f66902beb592d0901aa9af4f8d8de4a5072610df3cb9467703e4' 
  AND token = 'z4fzKwwV2ctICU7p0JpbJyLQUxl4iet5Jlbu9MiVi0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}