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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ee383d6d0556984490df1487e530cc27d289d72195625cbfd9d1495d7317c2' 
  AND token = 'k4gHvjVbEdZoRAg1AVWeG6xnABWttfWkgP+8FkN0zrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}