SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4563f81d0c44d8c72be70f1b2fa8a07523f7cc6561e752676b60109dd6ce1127' 
  AND token = 'Ln8TdtJ2MWH+A5MlMn4lG5arGC26cswsesT3BQMI4IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}