SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7290620d12290e2a077e15a854b2998dac1742c6412a20011ef2a48e535c1d5' 
  AND token = 'aRpOA1brrUkKnDqP1RQ13iu6hhixJu7LyjqgzN+BcYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}