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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2183078a110a6d5e5b6d20183901624b6bc91d58e35ee3cd57bd1d500e4cbda5' 
  AND token = 'n+pLy0ihGBERGqsVzFFw0Un6OsvWtJZ8SB/LP+wdHd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}