SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316c46fbd1e6b8f828b7adfdd7edb7661b3fe566038f7b0635c04ccddada041f' 
  AND token = 'ymqpOFQWYadzWEQWTM0QWNFLoIlU4qBXiVwrnBhfvRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}