SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5a75d17c7b2207ed01cbe43fea27af6d9b3ed173d18f39a508bc871151a656' 
  AND token = 'beN2o+JvdX+M5os/oxF2+vucqM/u9fcbKUtA0r1wnT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}