SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33a78a788c8364964764cd98fb8a4682d87ab7fc20f0e048077df89e7ce751a' 
  AND token = 'RdZT9qsRFCnNdIKkZd9yyDUmasISPJ1dszrCN8YNg3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}