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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd36da4ed46d0468c63204e34ac9247f7ac46419da4ff735b06ea2f7134a81c82' 
  AND token = 'rzlDRCljS0Vm5ZZ9coSAoYiRqeSGdZC4lOzRh69LGfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}