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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed7ccf04b39adac1d9e0573d9547cb66bfb7e2fffc622115b8521b2504dc3f1' 
  AND token = 'ufV7YIgMHHjFMc7XtfLqS9edJP4vFWovH9/D7IZKM1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}