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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2acb924d2896a3725bf9fedee72835f5597c7b29068b9eafc9a798c55e433e' 
  AND token = 'AUpOOW83tsO8KYVPpIjUj3g6PYdAg5KPxmYvurjeSk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}