SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d48561e95b22cf19551684ecd801c1c2fec98ef91ecb7f515d588b6e5d7044' 
  AND token = 'xOfoybyCehWYACqQVGT72184rp8vxkrOabjaDPlkwMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}