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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f155f539100a9f09584ceb42f220c2c5826a11da96154dd4d0826894cc83db6d' 
  AND token = 'cqtMizAxxB4SG2rJ+/v24IBCF97D/npK6jcWPy1juRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}