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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3468c5f3a2b9a49ec00b42643f65bd45c5672bb3b02e0504658211b04e2a8074' 
  AND token = '8K8JMqtNJRftX7RXwW0EnfZhNK1PemFHf7f4LKLJMFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}