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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d64e01eeabc3db6f9db25c5d379b1ad213ddb4e362c8c6402eba97cd73a4392' 
  AND token = '3NXm4xAD1N1P66Z2G38K7rqAC8s3uOFIzsYhuax5ZoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}