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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5d9ad5c1abe024964e74876a2ee9fb4cd2b79495c2a7b41e893e26008ba305' 
  AND token = 'Z0hA82zeOr1oMyLnl5n3orOeG5WokDxWQ4wFPgJVUZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}