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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a902b06bf91717b4bdc48f24b6bd35a63b7510850e455560537e00ce25b7d7' 
  AND token = 'E71/hWNFhJTwK0ahlXCR2c7OiPA2+9zw11nn17Kr2EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}