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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f785dc0b74deea111a4a07491d0791a62ffd10030d556c6970e37cd88d041d' 
  AND token = 'akSKopZKFyfHQZEGX+RAbikrmqLsKC0uj0t0g/ZEhns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}