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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373c2d9bdbe24a0c8bee46218f61f51072e56d303a3ef271a1ea315fe73e2a61' 
  AND token = 'wzAyQ7IIX9dEsUn4B5kBt7HFmjpXxa1SUNgnzfaGmu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}