SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131088337a2b7f0ece8f42d202cae8cf7d6046267a12470fa7b2f3e719315d4d' 
  AND token = 'u0fM+WXAObN57VIPDUB3PfXTx2OOG8uYlykdzg0bmDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}