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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbdb4386b73e5c97f949ba529e2012c640155fc6330bc9dc183d6969fca2d0c9' 
  AND token = '9Ap8RdocVfqWmIi7JdoPCq58SzpysJxirBZN43qWo3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}