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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e187ed8061bbfdf83c70e3a6410ff90b5743800a5d99376797d22b2077a9fcc' 
  AND token = 'MBp2rHL37I4PaP1Ac9ye+STI3z4FuVmW81Ye2xqcpKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}